The I.M. Rosenzweig Junior Investigator Award Winners​

The I.M. Rosenzweig Junior Investigator Award was established to encourage researchers to maintain and enhance their interest in PF research during the early stages of their academic career. 

The Albert Rose Established Investigator Award Winners

Created to allow established investigators to explore novel, innovative areas of research, the Albert Rose Established Investigator Award provides critical support to the development of new projects, and enables the investigator to pursue additional funding through the National Institutes of Health or other agencies. Two $50,000 grants are awarded per annual cycle, disbursed over a two-year period.

Linlin Gu, PhD

Apr 19, 2021, 14:56 PM
Title : Linlin Gu, PhD
First Name : Linlin
Middle Name :
Last Name : Gu, PhD
Position :
University : The University of Alabama at Birmingham
Proposal Title : Metabolic reprogramming and mitochondrial biogenesis are regulated by macrophage MCU in pulmonary fibrosis
Proposal Funder :
Dr. Linlin Gu is a researcher scientist in the Division of Pulmonary, Allergy, and Critical Care Medicine at the University of Alabama at Birmingham. He received his DVM and Ph.D. in the College of Veterinary Medicine, Yangzhou University, China. During his postdoctoral training in Dr. A. Brent Carter’s laboratory, he focused on investigating molecular mechanisms that lung macrophages utilize to induce the development and progression of pulmonary fibrosis. Dr. Gu found that the mitochondrial calcium uniporter (MCU), by regulating mitochondrial calcium influx, mediated pro-fibrotic polarization of lung macrophages that contributed to fibrosis progression. He has extended these studies to uncover that the regulation of macrophage bioenergetics by MCU facilitates macrophage apoptosis resistance in the development of pulmonary fibrosis.