PFF Insights

Respiratory Virus Season: 5 Facts that Matter

by By Jenny A. Williams, PA-C
October 24, 2025
viruses-and-fall-leaves

Fall has arrived and is in full swing! The fall season brings us pumpkin spice lattes, Halloween decorations, changing leaves, and cooler weather — but with all this change also comes respiratory virus season. Infections with viruses such as influenza, SARS-CoV-2 (COVID-19), and respiratory syncytial virus (RSV) can lead to undesired hospitalizations or ICU stays. Those living with pulmonary fibrosis are at increased risk of severe disease and complications, so it is important to stay aware during this time.

Here are 5 facts to keep you educated and prepared through this viral season.

1: Have you ever wondered why certain viruses are seasonal? There are many theories surrounding this topic. It is likely a culmination of multiple factors leading to this perfect storm we experience year after year. These mechanisms likely include specific virus preferences (such as humidity and temperature), human behavior (indoor activities, holiday travel, etc. during the fall and winter), and the effect of the changing weather on our immune systems and anti-viral defenses. Since we cannot change these factors easily, it is important to find other ways to prevent viral infections – such as getting your vaccinations, washing your hands frequently, avoiding those who are sick, and avoiding touching your face (eyes, nose, and mouth).  

2: The influenza virus is ever changing which is why it is important to get your flu vaccine every year. The CDC recommends everyone over the age of 6 months should get their annual influenza vaccination. If you are over the age of 65, it is recommended to get the high dose flu vaccine. The seasonal flu vaccine helps protect you from infection and can lessen the severity of symptoms if you do become ill. Contact your healthcare provider or go to your local pharmacy to get this done.

3: The respiratory syncytial virus (RSV) is particularly dangerous for infants and older adults, especially those with chronic respiratory diseases such as pulmonary fibrosis. The CDC recommends a onetime vaccine for RSV for those who are over the age of 75 or for anyone over the age of 50 at higher risk of severe infection. Talk to your health care provider or go to your local pharmacy and get your RSV vaccination.

4: Like the influenza virus, COVID-19 is ever evolving which requires updated vaccinations each season. The newest and most prevalent COVID-19 variants at present are the Stratus or XFG variant followed by the Nimbus or NB.1.8.1 variant.

5: In August 2025, the FDA approved the newest COVID-19 vaccinations from Pfizer-BioNTech, Moderna, and Novavax that will protect you from the most common variants we are seeing today. The FDA approved these for people who are over the age of 65 or less than the age of 64 and who are at high risk of severe infection (e.g. those with pulmonary fibrosis). These restrictions can make it more challenging for some to get the COVID-19 vaccine when it was previously easily accessible. If you do not fit these FDA guidelines, talk to your health care provider about getting the COVID-19 vaccination in clinic or getting a prescription to bring to your local pharmacy. Getting your COVID-19 vaccination is one of the most important things you can do to prevent severe disease, COVID-19 related hospitalization and death.